Mitochondrial calcium uniporter inhibition provides cardioprotection in pressure overload-induced he
《Heart failure》
Title：《Mitochondrial calcium uniporter inhibition provides cardioprotection in pressure overload-induced heart failure through autophagy enhancement》（译：《线粒体钙单向递质抑制通过自噬增强对压力超负荷引起的心力衰竭提供心脏保护作用》）
Abstract：Background: HF incurs high disease burden, and the effectiveness of known HF treatments is unsatisfactory. Therefore, seeking novel therapeutic target of HF is important. The present study aimed to investigate the role of the mitochondrial calcium uniporter (MCU) and its relationship with autophagy in overload-induced heart failure (HF).（译：背景：心衰会带来很高的疾病负担，而已知的心衰治疗方法的效果并不理想。因此，寻找治疗心衰的新靶点具有重要意义。本研究旨在探讨线粒体钙单转运蛋白（MCU）在超负荷性心力衰竭（HF）中的作用及其与自噬的关系。）
Periodical：International Journal of Cardiology
Impact Factor: 4.034
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Researcher：Ziqing Yu
Research unit：Department of Cardiology, Shanghai Zhongshan Hospital
Image and information：
Experimental information and images
Experiment 1
Model：C57BL / 6J mice_ heart failure Sham model
Imaging agent：FDG
Mode of administration：Tail vein administration
Data acquisition time：30min
Injection dose：363uci
Research image：Cardiac imaging was performed at the crosshairs
Experiment 2
Model：C57BL / 6J mice_ heart failure TAC+NS model
Imaging agent：FDG
Mode of administration：Tail vein administration
Data acquisition time：30min
Injection dose：396uci
Research image：Cardiac imaging was performed at the crosshairs
Experiment 3
Model：C57BL / 6J mice_ heart failure TAC+RR model
Imaging agent：FDG
Mode of administration：Tail vein administration
Data acquisition time：30min
Injection dose：418uci
Research image：Cardiac imaging was performed at the crosshairs
