Duodenal-Jejunal Bypass Ameliorates Type 2 Diabetes Mellitus by Activating Insulin Signaling and Imp

《II型糖尿病》

题目：《Duodenal-Jejunal Bypass Ameliorates Type 2 Diabetes Mellitus by Activating Insulin Signaling and Improving Glucose Utilization in the Brain》（译：《DJB 通过激活胰岛素信号传导和改善血糖大脑利用可改善Ⅱ型糖尿病》）
Abstract：Duodenal-jejunal bypass (DJB) can dramatically improve type 2 diabetes independent of weight loss and food restriction. Increasing evidence has demonstrated that brain insulin signaling plays an important role in the pathophysiology of type 2 diabetes. This study explores whether the antidiabetic effect of DJB is involved in brain insulin signaling activation and brain glucose utilization.（译：十二指肠空肠转流术（DJB）能显著改善2型糖尿病，与体重减轻和饮食限制无关。越来越多的证据表明，脑胰岛素信号在2型糖尿病的病理生理中起着重要作用。本研究探讨DJB的降糖作用是否与脑内胰岛素信号的激活和脑内葡萄糖的利用有关。）
期刊：Obesity Surgery
Impact Factor: 3.603
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研究作者：曲梅花
研究单位：潍坊医学院
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